1.Cas No: 1122-58-3
4.Melting point : 83-86 °C(lit.)
5.Boiling point: 211 °C
6.Density: 0.906 g/mL at 25 °C
7.Refractive index: n20/D 1.431
8.Storage conditions: Store in dark
Application:It is widely used as a catalyst for chemical synthesis, acylation, carbonylation, etherification and esterification in the synthesis of organic drugs, pesticides, dyes, food additives, etc. 4-Dimethylaminopyridine is a new type of high-efficiency catalyst widely used in chemical synthesis in recent years. The resonance of the electron-donating dimethylamino group with the parent ring (pyridine ring) in its structure can strongly activate the nitrogen atom on the ring for nucleophilic substitution.Remarkably catalyze the acylation (phosphorylation, sulfonylation, and carbonylation) of alcohols and amines with high steric hindrance and low reactivity and its activity is about 104-6 times that of pyridine. It has high catalysis in various types of reactions such as organic synthesis, drug synthesis, pesticides, medicine, dyes, perfumes, polymer chemistry, analytical chemistry, such as acylation, alkylation, etherification, esterification and transesterification. Ability to improve the yield is extremely obvious.
Category:Pyridine; Amino Acid; Coupling Reagents; Intermediates; Acylation Catalysts; Heterocyclic Building Blocks; Condensation Reagents; Chemical Reagents; General Reagents; Other Biochemical Reagents; Other Chemical Products; Organic Chemical Materials; Products; Chemical Materials-1; Organic Chemicals Raw materials; catalysts; chemical raw materials; other raw materials; pyridine and its derivatives; protected amino acids; pharmaceutical raw materials; raw materials; amines; other reagents; raw materials; organic acids; food additives; industrial raw materials; 4-dimethylaminopyridine; N,N-Dimethyl-4-pyridylamine; dimethylaminopyridine; biochemical reagents; acylation catalysts; chemical intermediates; pesticide intermediates; impurity reference materials; biochemicals; flavors and fragrances; products-pharmaceutical products; standard products;Intermediates-other intermediates; reagent peptides; Pyridine; Heterocycles; Pyridines, Pyrimidines, Purines and Pteredines; Pyridines derivates; Other Reagents; Biochemistry; Condensation & Active Esterification;Reagents for Oligosaccharide Synthesis.
We are Princechem Pharmaceutical manufacturer pass 20 years experience. Types of chemical reactions in are etherification, ammoniation, chlorination, esterification, cyclization, hydrogenation and Grignard reaction, etc..Over the past 10 years, more than 400 catalog products were developed. In recent years, more than 40 kinds of key pharmaceutical intermediates have been developed, involving anti-cancer, cardiovascular, digestive system, mental diseases and other fields. It includes the key intermediates of API such as Quetiapine, Fluvaxamine, Erlotinib, Gefitinib, Sunitinib, Lapatinib, Rabeprazole and Lafutidine. For many years, we have been providing high quality pharmaceutical intermediates for many world-famous pharmaceutical companies.
HI-Tech Enterprise was honored to YPC in 2011. The company adheres to scientific and technological innovation and has more than 10 authorized invention patents.
YPC insists on using the international standard management systems to promote our managements and have established the systems of ISO9001:2000, ISO14001:2004 and OHS18001:1999. Over the past few years, it has passed on-site audits by more than 20 international and domestic pharmaceutical companies.