1. CAS NO :50-23-7.
2. Molecular formula: C21H30O5.
4.Melting point: 211-214 °C(lit.)
5.Boiling point: 414.06°C (rough estimate).
6.Density: 1.0812 (rough estimate)
7.Refractive index: 1.6120 (estimate)
8.Flash point: 220°C.
9.Storage conditions: −20°C.
Chemical property: White or almost white crystalline powder, odorless, bitter taste. It deteriorates in light. Mp214-220 ℃ (decomposition); Specific rotation[ α] 25d + 157.5 ° (dioxane), + 176 ° (chloroform), + 162 ° - + 169 ° ; The ethanol solution has the maximum absorption at 242nm. This product is insoluble in water, insoluble in ether, slightly soluble in chloroform, soluble in acetone and ethanol. It is soluble in concentrated sulfuric acid and has green fluorescence. LD50 (rat, abdominal cavity) 150 mg / kg.
Application: Hydrocortisone-Calbiochem is mainly used for the replacement treatment of hypoadrenal function and the treatment of congenital adrenal hyperplasia, and also for rheumatoid arthritis, rheumatic hair fever, gout, asthma, allergic diseases, and can be used for severe infection and anti Huke treatment. Hydrocortisone-Calbiochem is also a kind of raw material for the preparation of several other important steroids.
We are Princechem Pharmaceutical manufacturer pass 20 years experience. Types of chemical reactions in are etherification, ammoniation, chlorination, esterification, cyclization, hydrogenation and Grignard reaction, etc..Over the past 10 years, more than 400 catalog products were developed. In recent years, more than 40 kinds of key pharmaceutical intermediates have been developed, involving anti-cancer, cardiovascular, digestive system, mental diseases and other fields. It includes the key intermediates of API such as Quetiapine, Fluvaxamine, Erlotinib, Gefitinib, Sunitinib, Lapatinib, Rabeprazole and Lafutidine. For many years, we have been providing high quality pharmaceutical intermediates for many world-famous pharmaceutical companies.
HI-Tech Enterprise was honored to YPC in 2011. The company adheres to scientific and technological innovation and has more than 10 authorized invention patents.
YPC insists on using the international standard management systems to promote our managements and have established the systems of ISO9001:2000, ISO14001:2004 and OHS18001:1999. Over the past few years, it has passed on-site audits by more than 20 international and domestic pharmaceutical companies.